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Dr. S. Mitchell Harman's Published Papers

Tan O, Harman SM, Naftolin F. What can we learn from design faults in the Women's Health Initiative randomized clinical trial? Bull NYU Hosp Jt Dis. 2009;67(2):226-9.

Salbe AD, Johnston CS, Buyukbese MA, Tsitouras PD, Harman SM. Vinegar lacks antiglycemic action on enteral carbohydrate absorption in human subjects. Nutr Res. 2009 Dec;29(12):846-9.

Davies SS, Traustadóttir T, Stock AA, Ye F, Shyr Y, Harman SM, Roberts LJ 2nd. Ischemia/reperfusion unveils impaired capacity of older adults to restrain oxidative insult. Free Radic Biol Med. 2009 Oct 1;47(7):1014-8.

Münzer T, Harman SM, Sorkin JD, Blackman MR. Growth Hormone and Sex Steroid Effects on Serum Glucose, Insulin, and Lipid Concentrations in Healthy Older Women and Men. J Clin Endocrinol Metab. 2009 Jul 14.

Miller VM, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, Naftolin F, Santoro N, Taylor HS, Harman SM. Using Basic Science to Design a Clinical Trial: Baseline Characteristics of Women Enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). J Cardiovasc Transl Res. 2009 Sep;2(3):228-239.

Harman SM, Brinton EA. Biphasic Effects of Hormone Treatment on Risk of Heart Disease. Menopausal Medicine, American Society for Reproductive Medicine's newsletter.

Harris DT, Badowski M, Harman SM. Treatment of Type I Diabetes in the NOD Mouse with Syngeneic Cord Blood Stem Cells. Open Stem Cell Journal Volume 1, 2009.

Traustadóttir T, Stock AA, Harman SM. High-dose statin treatment does not impair aerobic capacity or muscle function in older adults. A pilot study. Full abstract and Full text.

Tsitouras, PD, Gucciardo F, Salbe, AD, Heward CB, and Harman SM. High omega-3 fat intake improves insulin sensitivity and reduces CRP and IL6, but does not affect other endocrine axes in healthy older adults. Horm Metab Res. 2008 Mar;40(3):199-205.

Rodriguez A, Muller DC, Metter EJ, Maggio M, Harman SM, Blackman MR, Andres R (2007) Aging, androgens, and the metabolic syndrome in a longitudinal study of aging. J Clin Endocrinol Metab 92:3568-3572.

Muniyappa R, Sorkin JD, Veldhuis JD, Harman SM, Munzer T, Bhasin S, Blackman MR (2007) Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab 293:E769-775.

Harman SM. Estrogen replacement in menopausal women: Recent and current prospective studies, the WHI and the KEEPS. Gend Med. 3:254-269 (2006)

Muniyappa R, Wong KA, Baldwin HL, Sorkin JD, Johnson ML, Bhasin S, Harman SM, Blackman MR. Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men. J Clin Endocrinol Metab 2006 Nov;91(11):4445-52.

Münzer T, Rosen CJ, Harman SM, Pabst KM, St Clair C, Sorkin JD, Blackman MR. Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men. Am J Physiol Endocrinol Metab 2006 May;290(5):E1006-13.

Hougaku H, Fleg JL, Najjar SS, Lakatta EG, Harman SM, Blackman MR, Metter EJ. Relationship between androgenic hormones and arterial stiffness, based on longitudinal hormone measurements. Am J Physiol Metab 2006 Feb;290(2):E234-42.

Manson JE, Bassuk SS, Harman SM, Brinton EA, Cedars MI, Lobo R, Merriam GR, Miller VM, Naftolin F, and Santoro N. Postmenopausal hormone therapy: new questions and the case for new clinical trials. Menopause 2006 Jan-Feb;13(1):139-47.

Harman SM, Gucciardo F, Heward CB, Granstrom P, Barkley-White B, Rogers LW, and Ibarra JA, Jr. Discrimination of breast cancer by anti-malignin antibody serum test in women undergoing biopsy. Cancer Epidemiol Biomarkers Prev 2005 Oct;14(10):2310-5.

Harman SM. Testosterone in older men after the Institute of Medicine Report: where do we go from here? Climacteric 2005 Jun;8(2):124-35.

Harman SM, Brinton EA, Cedars M, Lobo R, Manson JE, Merriam GR, Miller VM, Naftolin F, Santoro N. KEEPS: The Kronos Early Estrogen Prevention Study. Climacteric 2005 Mar;8(1):3-12.

Harman SM, Brinton EA, Clarkson T, Heward CB, Hecht HS, Karas RH, Judelson DR, Naftolin F. Is the WHI relevant to HRT started in the perimenopause? Endocrine 2004 Aug;24(3):195-202.

Naftolin F, Taylor HS, Karas R, Brinton E, Newman I, Clarkson TB, Mendelsohn M, Lobo RA, Judelson DR, Nachtigall LE, Heward CB, Hecht H, Jaff MR, and Harman SM; The Women's Health Initiative could not have detected cardioprotective effects of starting hormone therapy during the menopausal transition. Fertil Steril 2004 Jun;81(6):1498-501.

Harman SM and Blackman MR. Use of growth hormone for prevention or treatment of effects of aging. J Gerontol A Biol Sci Med Sci 2004 Jul;59(7):652-8.

Harman SM, Liang L, Heward CB, Reaven P, Ping W, Cutler RL, and Duke R. Comparisons of Urinary Excretion of Three DNA Oxidation Adducts and Isoprostane F2a Measured by Liquid Choromatography-Mass Spectrometry in Smokers, Ex-smokers, and Non-smokers. Free Radic Biol Med 2003 Nov 15;35(10):1301-9.

Hecht HS and Harman SM. Comparison of the effects of atorvastatin versus simvastatin on subclinical atherosclerosis in primary prevention, as determined by electron beam tomography. Am J Cardiol 2003 Jan 1;91(1):42-5.

Harman SM. The Kronos Longevity Research Institute. Exp Gerontol 2003 May;38(5):483-7.

Liang Y, Wei P, Duke R, Reaven P, Harman SM, Cutler RG, and Heward CB. Quantification of 8-iso-Prostaglandin-F₂ and 2,3-dinor-8-iso-Prostaglandin-F₂ in Human Urine using Liquid Chromatography-Tandem Mass Spectrometry. Free Radic Biol Med. 2003 Feb 15;34(4):409-18.

Harman SM and Blackman MR. The effects of growth hormone and sex steroid on lean body mass, fat mass, muscle strength, cardiovascular endurance and adverse events in healthy elderly women and men. Horm Res. 2003;60(Suppl 1):121-4.

Blackman MR, Sorkin JD, Münzer T, Bellantoni MF, Busby-Whitehead J, Stevens TE, Jayme J, O'Connor KG, Christmas C, Tobin JD, Stewart KJ, Cottrell E, St. Clair C, Pabst KM, and Harman SM. Effects of growth hormone and sex steroid administration in healthy aged women and men. JAMA 2002 Nov 13;288(18):2282-92.

Münzer T, Harman SM, Hees P, Shapiro E, Christmas C, Bellantoni MF, Stevens T, O'Connor KG, Pabst KM, St.Clair C, Sorkin JD, and Blackman MR. Effects of GH and/or sex steroid administration on abdominal subcutaneous and visceral fat in healthy aged women and men. Metab 2001 Aug;86(8):3604-10 J Clin Endocrinol.

Gusenoff J, Harman SM, Veldhuis JD, Jayme JJ, St. Clair C, Münzer T, Christmas C, O'Connor KG, Stevens TE, Bellantoni MF, Pabst K, and Blackman MR. Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men. Metab 2001 Apr;280(4):E616-25 Am J Physiol Endocrinol.

Harman SM, Metter EJ, Tobin JD, Pearson J, and Blackman MR. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. Metab 2001 Feb;86(2):724-31 J Clin Endocrinol.

O'Connor KG, Tobin JD, Harman SM, Plato CC, Roy TA, Sherman SS, and Blackman MR.Serum levels of insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostate-specific antigen as predictors of clinical prostate cancer. Metab 2000 Nov;85(11):4258-65 J Clin Endocrinol.

Moffatt SD, Zonderman AB, Harman SM, Blackman MR, and Resnick SM. The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older men. Arch Intern Med 2000; 160:2193-8.

Marcell TJ, Harman SM, Urban RJ, Metz DD, Rodgers BD, and Blackman MR. Comparison of GH, IGF-I, and testosterone with mRNA of receptors and myostatin in skeletal muscle in older men. Am J Physiol (Endocrinol Metab) 2001; 281:E1159-64.

Christmas C, O'Connor KG, Harman SM, Tobin JD, Münzer T, Bellantoni MF, St. Clair C, Pabst KM, Sorkin JD, and Blackman MR. Growth hormone and sex steroid effects on bone metabolism and bone mineral density in healthy aged women and men. J Gerontol 2002; 57A: M12-8.