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Progress in Longevity Medicine Seminar Series
Luigi Ferrucci, MD, PhD
Director, Baltimore Longitudinal Study of Aging
Senior Investigator, Clinical Research Branch
National Institute on Aging, National Institutes of Health
Date/Time: Friday, March 10, 2006; 6:00 pm (dinner included)
Location: The Arizona Club, 201 North Central Avenue, 37th Floor
Cost: Free
Abstract: Metabolism, the continuous conversion between structural molecules and energy, is life in essence. Size, metabolic rate, and maximum life span appear to be inextricably interconnected in all biological organisms and almost following a "universal" low. The notion of metabolic rate as the natural "rate of living" filled most of the academic discussion on aging in the early twentieth century to be later substituted by the free-radical theory of aging.
We argue that the rate of living theory was discarded too quickly and that studying factors affecting resting metabolic rate (RMR) over the aging process may provide great insight into the core mechanisms explaining differential longevity between individuals, and possibly the process leading to frailty. We predict that measures of RMR will be introduced in geriatric clinical practice to gather information on the degree of multi-system dysregulation, exhaustion of energy reserve, and risk of irreversible frailty.
Objectives:
Biography: Dr. Luigi Ferrucci, a geriatrician and epidemiologist, is the Director of the Baltimore Longitudinal Study of Aging, and a Senior Investigator at the Clinical Research Branch of the National Institute on Aging, National Institutes of Health. Dr. Ferrucci has made major contributions in the design of many epidemiological studies conducted in the U.S. and in Europe, including the European Longitudinal Study on Aging, the "ICare Dicomano Study," the AKEA study of Centenarians in Sardinia, and the Women's Health and Aging Study. His research interests involve frailty and mobility disability in the elderly.
He was previously a member of the Department of Geriatric Medicine of the National Institute for Research and Care of the Elderly (INRCA) in Florence, Italy. Dr. Ferrucci was also a visiting scientist at the National Institute on Aging (NIA), where he worked as a researcher for the Established Populations for Epidemiological Studies of the Elderly and a Co-Investigator for the Women's Health and Aging Study. He has been newly appointed to the position of Editor-in-Chief of the Journal of Gerontology: Medical Sciences.
Dr. Ferrucci received his medical degree at the University of Florence, where he also earned his doctorate of philosophy degree in Biology and Pathophysiology of Aging. He completed his internship in the intensive care unit of the Institute of Gerontology and Geriatrics of the University of Florence and became a fellow at INRCA. Dr. Ferrucci was Assistant Director and Coordinator of the Laboratory of Clinical Epidemiology at the INRCA's Geriatric Department.
Dr. Ferrucci has written or co-authored more than 250 articles and more than 30 book chapters, and is co-editor of two books.
To RSVP or for additional information, please contact Diana Vuong at (602) 778-7492 or via email, Diana.Vuong@kronosinstitute.org.
"This program is accredited by the Accreditation Council for Continuing Medical Education and designates this educational activity for 1 hour in Category 1 credit toward the AMA Physician's Recognition award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity."
CME Credit is available through University of Arizona, College of Medicine to attendees;
Sponsored by the University of Arizona College of Medicine at the Arizona Health Sciences Center
The Endeavor of High Maintenance Homeostasis: Resting Metabolic Rate and Legacy of Longevity
Luigi Ferrucci, MD, PhD
Director, Baltimore Longitudinal Study of Aging
Senior Investigator, Clinical Research Branch
National Institute on Aging, National Institutes of Health
Date/Time: Friday, March 10, 2006; 6:00 pm (dinner included)
Location: The Arizona Club, 201 North Central Avenue, 37th Floor
Cost: Free
Abstract: Metabolism, the continuous conversion between structural molecules and energy, is life in essence. Size, metabolic rate, and maximum life span appear to be inextricably interconnected in all biological organisms and almost following a "universal" low. The notion of metabolic rate as the natural "rate of living" filled most of the academic discussion on aging in the early twentieth century to be later substituted by the free-radical theory of aging.
We argue that the rate of living theory was discarded too quickly and that studying factors affecting resting metabolic rate (RMR) over the aging process may provide great insight into the core mechanisms explaining differential longevity between individuals, and possibly the process leading to frailty. We predict that measures of RMR will be introduced in geriatric clinical practice to gather information on the degree of multi-system dysregulation, exhaustion of energy reserve, and risk of irreversible frailty.
Objectives:
- To explore the energetic pathway to frailty
- To understand the relationship between longevity and resting metabolic rate (RMR)
- To propose a model for studying the metabolic cost of walking
Biography: Dr. Luigi Ferrucci, a geriatrician and epidemiologist, is the Director of the Baltimore Longitudinal Study of Aging, and a Senior Investigator at the Clinical Research Branch of the National Institute on Aging, National Institutes of Health. Dr. Ferrucci has made major contributions in the design of many epidemiological studies conducted in the U.S. and in Europe, including the European Longitudinal Study on Aging, the "ICare Dicomano Study," the AKEA study of Centenarians in Sardinia, and the Women's Health and Aging Study. His research interests involve frailty and mobility disability in the elderly.
He was previously a member of the Department of Geriatric Medicine of the National Institute for Research and Care of the Elderly (INRCA) in Florence, Italy. Dr. Ferrucci was also a visiting scientist at the National Institute on Aging (NIA), where he worked as a researcher for the Established Populations for Epidemiological Studies of the Elderly and a Co-Investigator for the Women's Health and Aging Study. He has been newly appointed to the position of Editor-in-Chief of the Journal of Gerontology: Medical Sciences.
Dr. Ferrucci received his medical degree at the University of Florence, where he also earned his doctorate of philosophy degree in Biology and Pathophysiology of Aging. He completed his internship in the intensive care unit of the Institute of Gerontology and Geriatrics of the University of Florence and became a fellow at INRCA. Dr. Ferrucci was Assistant Director and Coordinator of the Laboratory of Clinical Epidemiology at the INRCA's Geriatric Department.
Dr. Ferrucci has written or co-authored more than 250 articles and more than 30 book chapters, and is co-editor of two books.
To RSVP or for additional information, please contact Diana Vuong at (602) 778-7492 or via email, Diana.Vuong@kronosinstitute.org.
"This program is accredited by the Accreditation Council for Continuing Medical Education and designates this educational activity for 1 hour in Category 1 credit toward the AMA Physician's Recognition award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity."
CME Credit is available through University of Arizona, College of Medicine to attendees;
Sponsored by the University of Arizona College of Medicine at the Arizona Health Sciences Center
Phone: (866) 840-1117 - Fax: (602) 778-7490 - Email: info@kronosinstitute.org
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