Source: Kronos Longevity Research Institute website (www.KronosInstitute.org) Sep 9, 2010

Longevity E-Kronicle

The Longevity E-Kronicle, KLRI's quarterly e-newsletter, is a compilation of the most recent research findings in longevity, hormones, nutrition, diabetes, exercise, and other relevant research on age-related diseases. Each issue contains a shortened version of the full abstract and links to the full article. Click on the links below to view past issues of our e-newsletter.

Volume 3-2009
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Headlines
  • Family Testing of Congenital Heart Disease (CHD) Does Not Mean Family Member May Have CHD
  • High Blood Pressure Creates Greater Risk of Cognition in Men and Women 65 to 74 Years of Age
  • Men with Low to Normal Testosterone Levels Have Increased Risk of Stroke and Transient Ischemic Attack
  • Six Out of 10 Deaths From Cardiovascular Disease Can be Prevented
  • Vitamin D, Calcium and Physical Activity are Critical for Double-Diseased Burdened Individuals
  • Popular Choices Mandates To Make Food Content Healthier
  • Calorie Restriction Increases Overall Physical Activity
  • Fish Oil May Alter the Immune Response to Influenza Infection
  • High-dose Oral Vitamin D3 Supplementation in the Elderly Rapidly and Safely Increases 250 Hydroxyvitamin D Level
  • Telomere Length-An Informative Biomarker of Healthy Aging
  • Women Are Biologically Stronger Than Men
  • Type 2 Diabetes and Other Cardiovascular Disease Risk Were Not Increased Due to Menopause
  • Frequency of Serious Complications in Patients with Type 1 Diabetes Decrease Due to Treatment
  • Potential Interventions in Type 2 Diabetes for Significant Public Health Impact
  • Lifestyle Intervention May Be Cost-Effective for Diabetes Patients
  • Higher Noncalcified Plaque in Patients with Type 2 Diabetes vs. Type 1 Diabetes
  • Reduction of Blood Glucose and Insulin are Independent to Anti-Inflammatory Effect in Type 2 Diabetes
  • Short-term Aerobics Positively Impacts Arterial Thickness Caused by Type 2 Diabetes and/or Hypertension
  • Adult Offspring of Women with Diet-Treated Type 1 Diabetes are at Risk for Metabolic Syndrome
  • Tai Chi Improves Motor Ability in the Elderly
  • A 30-day Period of Interruption of Physical Activity Did Not Alter the Values of Physical Capacity of Active Women
  • Swim Training in Mice Retarded the Development of Ehrlich Tumors
  • Exercise in a Warm Environment Mitigates the Post-Exercise Fall in Cardiac Output
  • A Year Long Exercise Intervention Decreases C-Reactive Protein Among Obese Post Menopausal Women
  • The Expenditure of Physical Activity Energy Increased During Extended Exercise
  • Effects of Lean and Fat Mass on Bone Mineral Density and Arterial Stiffness in Elderly Men
  • Gabapentin Appears to be Favorable For Hot Flushes
  • Testosterone Enhances Cognition Effect in Rats
  • Postmenopausal Women With No Bleeding Do Not Require Automatic Testing
  • Lower Dosages and Non-Oral Routes Used For HT Since 2002
  • Low Risk Postmenopausal Diabetic Women Should Be Offered Appropriate Hormone Therapy
  • Salivary Testing Does Not Reduce the Same Results As Serum in Post Menopausal Women
  • Low Dose Conjugated Estrogens Cream Used Daily or Twice a Week Relieves Symptoms in Postmenopausal Women
  • Synthetic Conjugated Estrogens Vaginal Cream Effects in Treating Vaginal Atrophy
  • Age and Depression Have an Effect on Cognitive Function
  • Prevalence of Erectile Dysfunction in Men Screened for Prostate Cancer
  • 90% of Women over 60 and Men over 50 May Need Statin Treatment
  • Heightening Level of Lipid Peroxidation and High Level of Copper Could Increase Cardiovascular Risk

Volume 2-2009
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Headlines
  • Older Adults Have the Highest Prevalence of Metabolic Syndrome
  • HDL Increases In American Women But Not In Chinese Women
  • Body Mass Index and Waist Circumference May Be a Mischaracterization for Patterns of Abs Fat
  • Underweight Older Adults May Be Susceptible to Cardiac Events Post Op After Hip Fracture
  • Failure to Recognize the Immune System's Role in Chronic Heart Failure
  • Abdominal Fats Is Not Impacted By Menopause
  • Dried Plums May Restore Bone Mineral Density
  • Vitamin D Recommendations Too Low To Address Vitamin D Insufficiencies
  • Men And Women Needs And Wants Differ During Home Health Care Services
  • The Aging Population--Is There A Role For Endocrine Interventions?
  • Oxidative And Nitrosative Are Associative Factors Of Neurodegenerative Diseases
  • Long-term Endurance Positively Effective In Patients With Type 2 Diabetes Mellitus
  • Peak Exercise Oxygen Consumption and Heart Failure Survival Score Predict Survival in Heart Failure Patients
  • Volume Of Exercise And Fitness Nonresponse In Sedentary, Postmenopausal Women
  • Unusual Pedometers Worked Better For Step Count
  • Physical Activity, Menopause, And Quality of Life: The Role of Affect and Self-Worth Across Time
  • Fracture Risk Increases After Diagnosis of Breast or Other Cancers In Postmenopausal Women: Results From the Women's Health Initiative
  • Lactate Accumulation During Exercise And Increased Fatigued Resistance Caused By Aging
  • Topical Estrogen Therapy Relieves Vaginal Atrophy Symptoms
  • Decline in Hormone Use Over 17 Years
  • Using A Balance Strategy Training Program
  • Low Testosterone And Anaemia In Men with Type 2 Diabetes
  • Androgen Deprivation Therapy
  • Growth Hormone Deficient Adults
  • Estrogen and Glucose Intolerance
  • Psychological Symptoms in Surgically Induced Menopausal Women
  • Hot Flashes Impacts Women's Quality of Life
  • Sexual Experience and Estrogen
  • Nonhormonal Therapies Used For Menopausal Symptoms
  • Some Herbal Formulas Did Not Impact Menopausal Symptoms
  • Chemotherapy For Breast Cancer Did Not Increase Older Women's Chance of Getting Dementia
  • Study Suggests Caution When Diagnosing Metabolic Syndrome
  • The Value of Family History As A Risk Indicator For Venous Thrombosis
  • Metabolic Syndrome and Obesity Potential Predictors of Depressive Symptoms
  • Hysterectomy Is More Likely To Be Performed In Heavier Women
  • Moderate Alcoholic Beverage Consumption Had Minimal Impact on Insulin Sensitivity
  • Telomerase Insufficiency In Rheumatoid Arthritis

Volume 1-2009
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Headlines
  • Chronic Inflammation is a Major Risk of Aging
  • Telomere Shortening May Be Caused by Oxidative Stress
  • Decreased Heart Rate in Mammals Reduced Risk of Deaths
  • The Effectiveness of Beta-Blockers was Similar to Survival Rate
  • Elevated BMI Linked to Heart Failure
  • Exercise Increase GH Secretion Whether Continuous or Intermittent Anxiety
  • Reduced by Physical Activities in Older Adults
  • Growth Hormones-Differences in Stress Resilience
  • Is Taller Healthier?
  • Changes That Contribute to Age-Related Muscle Dysfunction
  • Some Dosages of Vitamin C and Vitamin E Are Not Sufficient to Decrease LDL Level Older Adults with Type 2 Diabetes
  • Long-term Low Dose Aspirin Does Not Prevent Development of Clinical Type 2 Diabetes
  • Raisins and Walking May Reduce LDL
  • Green Tea Polyphenols Affects the Total HDL Cholesterol
  • Mediterranean Diet and Nuts - A Useful Tool for Metabolic Syndrome
  • Omega-3 May Affect Weight and Appetite in Alzheimer's Patients
  • Estrogen Effect on IGF-I is Subject to Method of Administration
  • Women's Well-Being Is Not Always Affected By Menopausal Transition and Postmenopause
  • Higher Levels of Endogenous Sex Hormones Preserve Brain Function in Older Men
  • Primary and Secondary Hand Smoke May Cause Early Onset of Menopause
  • The Effects of Various Aspects of Smoking and Menopause
  • Endogenous Estradiol Level Effects on Bone Mineral Density May Be More Effective in Older Women
  • The Relationship Between Life-space and Cognitive Function
  • Omega-3 May Delay Cognitive Decline
  • Is There a Benefit of Cholesterol Lowering in Cognitive Function?
  • Caloric Restriction May Be Beneficial In Bone Mass and Bone Quality
  • Omega-3 and Caloric Restriction May Prevent Age-Dependent Loss of LDLr Membrane
  • Sample Recruitment Methods Can Seriously Affect the Outcome of Studies in Older Adults
  • Improved Communication Needed Between Primary Care Physicians and Total Joint Arthroplasty Patients

Volume 3 - 2008
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Headlines
  • Multiple Food Groups Influence Diabetes
  • High Intake of Vitamin C is Associated with Lower Bone Loss
  • Dark Chocolate and C-Reaction Protein
  • Calorie Restriction Minimizes Activation of Insulin Signals
  • Resveratrol-containing Nutraceutical Mixture Mimics Gene Expression of Caloric Restriction
  • Subclinical Atherosclerosis Evaluated
  • Effects of Hormone Replacement Therapy and Coffee
  • Transdermal Estradiol May Reduce Oxidative Stress In Postmenopausal Women
  • Effects of Physical Exercises and Estrogen Therapy on Health-Related Quality of Life
  • Older Men with Low Serum Estradiol Have an Increased Risk of Fractures
  • Risk Factors For the Onset of Menopausal Symptoms
  • The Hot Flush Beliefs Scale
  • Bone Mineral Density at Menopause Does not Predict Breast Cancer Incidence
  • Bone Turnover Marker Profile in Relation to the Menstrual Cycle of Premenopausal Healthy Women
  • Identifying Meaningful Differences in Vasomotor Symptoms Among Menopausal Women
  • Type 2 Diabetes and Glycemic Control in African Americans
  • The Relationship of Reduced Nerve Function and Diabetes with Physical Performance
  • The Decline in Early Mortality in Men and Women with Type 2 Diabetes
  • Differences in Treadmill Exercise Tolerance
  • Self-reported Distress After Cognitive Testing in Patients
  • The Developmental Origins of Sarcopenia
  • Moderate Impact Exercise on Skeletal Integrity in Master Athletes
  • Screening for Osteoporosis in Men: A Clinical Practice Guideline from the American College of Physicians
  • Cognitive Decline During Aging
  • The Importance of Daytime Movement
  • Impact of Genetics on Low Bone Mass in Adults
  • Patient Ethnicity and the Identification of Anxiety in Elderly
  • Frailty in Older Mexican-American and European-American Adults
  • The Importance of Daytime Movement

Volume 2 - 2008
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Headlines
  • Low-Fat or Mediterranean-Style Diet Reduces Cardiovascular Events
  • Dietary Calcium and Dairy Products Suppress Oxidative and Inflammatory Stress
  • Fish Oil Supplementation Enhances Memory Performance
  • Biomarkers of Inflammation and Malnutrition Predict Early Death
  • Growth Hormones Can Enhance Vascular Health in Older Adults
  • Lipid Levels Predict Risk of Coronary Heart Disease While on Hormone Therapy
  • Testosterone Therapy Improves Sexual Function in Postmenopausal Women
  • Prolactin and Cortisol Increase During Nighttime in Postmenopausal Women
  • The Effects of Different Hormone Replacement Therapies
  • Declining Estrogen Levels During Menopause Increases Risk of Cardiovascular Disease
  • Poor Quality of Life Does Not Affect Likelihood of Starting Hormone Therapy
  • High Intensity Exercise Enhances Capacity to Oxidate Carbohydrates
  • Physical Fitness Does Not Affect C-Reactive Protein Levels
  • The Management of Myocardial Infarction Is The Same for Men and Women
  • Exercise Blood Pressure Predicts Incident Cardiovascular Disease
  • Obesity Is Prevalent In Most Racial Groups
  • Testosterone Deficiency Common in Men with Diabetes
  • Insulin-like Growth Factor Binding Protein 1 Are Involved in Insulin-like Activity
  • Diabetic Patients with a Diabetic Foot are at a Higher Risk for Cardiovascular Disease
  • Statin Use Has No Effect On Frailty
  • Osteoporosis is Prevalent in Turkey

Volume 1 - 2008
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Headlines
  • Oxidative Stress Leads to Tissue Deterioration and Aging
  • Women Who Are Healthy and of Normal Weight Have a Life Expectancy of Another 22.1 Years
  • Long-Term Physical Activity In Older Adults Preserves Antioxidant Capacity
  • Exercise Training Improves Glycemic Control and Oxidative Stress
  • Fat Increases in Trunk and Arms of Postmenopausal Women
  • Fatty Fish Influences Muscle Function in Older Men and Women
  • More Studies Need to Assess the Effect of Obesity on Physical Activity
  • Low Vitamin D Levels Are Common in the Elderly
  • Growth Hormone Improved Maximal Oxygen in Growth Hormone Deficient Adults
  • Testosterone Increases Total Fat Free Mass and Total Body and Thigh Muscle
  • Transdermal Patch Believe to Relieve Symptoms of Vulvovaginal Atrophy
  • OB/GYN Should Work to Identify At-Risk Perimenopausal Women
  • The Role of Inflammation in Coronary Artery Calcification
  • Physicians Have Been Sensitized To the Potential of a Missed Diagnosis of Acute Coronary Syndrome
  • Advanced Coronary Artery Calcium Identified a Set of Lower-Risk Women as High Risk for Cardiovascular Diseases
  • Insulin Resistance of Protein Metabolism Differs in Men and Women

Volume 3 - 2007
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Headlines
  • The Effects of Aging and Physical Activity on Doppler Measures of Diastolic Function
  • Effect of Aerobic Exercise Training on Serum Levels of High-Density Lipoprotein Cholesterol: A Meta-analysis
  • Enhancement of Fat Metabolism by Repeated Bouts of Moderate Endurance Exercise
  • Genealogy of Centenarians and Their Relatives: A Study of 12 Families
  • Extended Longevity of Queen Honey Bees Compared to Workers is Associated with Peroxidation-Resistant Membranes
  • Low Vitamin D Status Despite Abundant Sun Exposure
  • Dietary Phytoestrogen Intake and Cognitive Function in Older Women
  • Body Size and Shape Changes and the Risk of Diabetes in the Diabetes Prevention Program
  • Accelerated Loss of Skeletal Muscle Strength in Older Adults with Type 2 Diabetes: The Health, Aging, and Body Composition Study
  • What Is the Best Predictor of Future Type 2 Diabetes?
  • Effect of Estradiol-Drospirenone Hormone Treatment on Myocardial Perfusion Reserve in Postmenopausal Women with Angina Pectoris
  • Night Sweats, Sleep Disturbance, and Depression Associated with Diminished Libido in Late Menopausal Transition and Early Postmenopause: Baseline Data From the Herbal Alternatives for Menopause Trial (HALT)
  • Growth Hormone Regulation of p85alpha Expression and Phosphoinositide 3-Kinase Activity in Adipose Tissue: Mechanism for Growth Hormone — Mediated Insulin Resistance
  • Estrogen Effects on Arteries Vary With Stage of Reproductive Life and Extent of Subclinical Atherosclerosis Progression
  • Residual Lifetime Risk of Fractures in Women and Men

Volume 2 - 2007
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Headline
  • Arterial Plaque Significantly Reduced In Women Age 50-59 Taking Hormones, Says New Analysis Of Women's Health Initiative Data

Volume 1 - 2007
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Headlines
  • Gray Is the New Gold: Longevity Science and the Flourishing Aging Society
  • Types of Stents Used Shows No Differences By Gender
  • Use of Dietary Supplement is Common by Americans for Coronary Artery Disease
  • Garlic Has Not Been Shown to Lower LDL Cholesterol
  • Sex Hormones with C-Reaction Protein Increases Total Bioavailable Hormones in Men
  • Progesterone Does Not Cause Oedema, Study Shows
  • No Cardiac Affects Shown With the Use of DHEA
  • Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1 to Benefit the Interior Walls of the Heart
  • Low Body Mass, An Independent Risk Factor For Lower Testosterone
  • Health and Lifestyle May Affect Age-Related Hormones
  • High Levels of Adiponectin Equals Lower Risk of Coronary Heart Disease
  • Soy Isoflavones Do Not Affect Bone Resorption
  • Type 1 Diabetes, New Intervention May Open Door to Prediction and Prevention
  • DHEA Does Not Improve Insulin Secretion
  • Growth Hormones May Play a Role in Cognitive Performance
  • Vitamin D Reduces the Number of Falls in Nursing Homes
  • Risks of Hip Fracture Relative to Menopause


Kronos Longevity Research Institute
2390 E. Camelback Rd., Ste. 440 Phoenix, AZ 85016
Phone: (866) 840-1117   -   Fax: (602) 778-7490   -   Email: info@kronosinstitute.org